Diabetes

Diabetic Neuropathy (Nerve Problems)

What is diabetic neuropathy?
Diabetic neuropathy is a nerve disorder, a complication of diabetes. It can lead to problems throughout the body.

People with diabetes can develop nerve problems at any time, but significant clinical neuropathy can develop within the first 10 years after receiving a diabetes diagnosis. The risk of developing neuropathy increases the longer a person has diabetes. About 60 percent of people with diabetes have some form of neuropathy.

What causes diabetic neuropathy?
Although the exact causes of diabetic neuropathy are unknown, several factors may contribute to the disorder, including the following:

  • high blood glucose
    High blood glucose causes chemical changes in nerves and impairs the nerves' ability to transmit signals. It also has the potential to damage blood vessels that carry oxygen and nutrients to the nerves.

  • inherited factors
    There are some genetic traits that may make some people more susceptible to nerve disease than others.

What are the symptoms of diabetic neuropathy?
The following are the most common symptoms for diabetic neuropathy, however, each individual may experience symptoms differently. Symptoms include:

  • numbness in the hands or feet
  • pain in the hands, feet, or legs
  • problems with internal organs such as the digestive tract, heart, or sexual organs causing:
  • indigestion
  • diarrhea or constipation
  • dizziness
  • bladder infections
  • impotence
  • weakness
  • weight loss
  • depression

The symptoms of diabetic neuropathy may resemble other conditions or medical problems. Consult your physician for a diagnosis.

What are the different types of diabetic neuropathy?

diffuse neuropathy is neuropathy that affects many parts of the body, and includes:
diffuse peripheral neuropathy is neuropathy that affects nerves in the extremities:
  • legs
  • feet
  • arms
  • hands

Symptoms include:

  • numbness
  • insensitivity to pain or temperature changes
  • tingling, burning, or prickling
  • sharp pains or cramps
  • extreme sensitivity to touch
  • loss of balance or coordination
diffuse autonomic neuropathy is neuropathy that affects nerves that serve internal organs, processes, and systems of the:
  • heart
  • digestive system
  • sexual organs
  • urinary tract
  • sweat glands

Symptoms include:

  • incontinence
  • digestive problems
  • low blood pressure
  • dizziness
  • fainting
  • impaired perception of pain
  • hypoglycemia
  • profuse sweating
focal neuropathy is neuropathy that affects a single, specific nerve and part of the body, such as the: 
  • eyes
  • facial muscles
  • hearing
  • pelvis and lower back
  • thigh
  • abdomen

Symptoms include:

  • pain in front of thigh
  • severe pain in lower back or pelvis
  • pain in chest, stomach, or flank
  • chest or abdominal pain that mimics angina, heart attack, or appendicitis
  • aching behind eye
  • inability to focus eye
  • double vision
  • paralysis on one side of face
  • hearing problems
How is neuropathy diagnosed?
In addition to a complete medical history and physical examination, the physician may:
  • check muscle strength
  • check muscle reflexes
  • check muscle sensitivity to:
  • position
  • vibration
  • temperature
  • light touch
  • request additional tests, such as:
  • nerve conduction studies to check flow of electrical current through a nerve
  • electromyography to see how muscles respond to electrical impulses
  • ultrasound to see how parts of the urinary tract are functioning
  • nerve biopsy to remove a sample of nerve for examination

Treatment for neuropathy:
Specific treatment will be determined by your physician(s) based on:

  • your age, overall health, and medical history
  • extent of the disease
  • your tolerance for specific medications, procedures, or therapies
  • expectations for the course of the disease
  • your opinion or preference

The goal of treatment is to relieve pain and discomfort, as well as to prevent additional tissue damage. Treatment may include:

  • pain medications
  • antidepressant medications
  • topical creams
  • transcutaneous electronic nerve stimulation (TENS) therapy
  • hypnosis
  • relaxation training
  • biofeedback training
  • acupuncture

Treatment may also be prescribed for complications of neuropathy, such as gastrointestinal problems, dizziness and weakness, and urinary or sexual problems.

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